Evaluation and Management of Virologic Failure
10 questions
Questions in Topic
- 1. Indications for Resistance Testing
- 2. Impact of M184V Mutation on NRTIs
- 3. Impact of M184V on INSTI-Based Regimens
- 4. Thymidine Analog Mutations (TAMs)
- 5. K103N Mutation
- 6. Virologic Failure while Taking Rilpivirine
- 7. Doravirine Resistance
- 8. Darunavir Dosing with Prior Use of Protease Inhibitor
- 9. Elvitegravir Resistance
- 10. Maraviroc Resistance
Learning Objectives
- Recognize when persons taking antiretroviral therapy are in virologic failure based on HIV RNA levels
- Identify virologic failure and collaboratively employ appropriate resistance testing
- Utilize an HIV resistance database tool to assist in the optimal selection of regimens in persons with HIV drug resistance
- Differentiate drug resistance profiles based on antiretroviral drug classes
- Identify key factors including pharmacokinetic issues when selecting a salvage antiretroviral regimen in persons with virologic failure
Authors
Reviewers
4th Edition
This is a substantial revision of the original Question Bank Topic. The previous edition was titled Evaluation and Management of Virologic Failure and was available until August 31st, 2026.
CE
Continuing Education
This activity qualifies for:
To access or download CE transcript, view CE Notices for instructions.
- 1.0 CME AMA PRA Category 1 Credit™
- 1.0 CNE contact hour
- 1.0 Pharmacotherapeutic/Pharmacology CE contact hour
- 1.0 CPE knowledge-based contact hour
UAN: JA0000297-9999-26-037-H99-P - 1.0 CE/Non-Physician Attendance credit
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CME and CNE Origination: June 1st, 2017
CME, CNE, CPE, and IPCE* Review: September 1st, 2026
CME, CNE, CPE, and IPCE* Expiration: August 31st, 2029 (4th Edition)
* If CPE or IPCE is available
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