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Evaluation and Management of Virologic FailureQuestion 1/10

A 24-year-old man with moderate baseline renal insufficiency is seen in clinic for a routine follow-up visit. He describes having problems consistently taking the antiretroviral regimen rilpivirine-tenofovir alafenamide-emtricitabine. Laboratory studies are ordered and show an HIV RNA level of 875 copies/mL, which is an increase from the last visit when it was undetectable.

At this point, which one of the following is the best choice regarding HIV drug-resistance testing for this patient?

Figure 1. Indications for HIV Drug Resistance Testing
Source: Panel on Antiretroviral Guidelines for Adults and Adolescents. Guidelines for the use of antiretroviral agents in adults and adolescents with HIV. Department of Health and Human Services. Laboratory testing: drug-resistance testing. March 23, 2023.
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Question Last Updated
February 1st, 2025

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