Antiretroviral Therapy

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Antiretroviral Therapy
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Lesson 3. Drug Interactions with Antiretroviral Medications

Antiretroviral Therapy

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Drug Interactions with Antiretroviral Medications Overview

About this Lesson

Last Updated: February 3rd, 2025

CNE/CME Continuing Education

This lesson qualifies for:
  • 1.5 CME AMA PRA Category 1 Credits™, or
  • 1.5 CNE contact hours and 1.5 CE contact hours (qualifies for pharmacology CE for advanced practice nurses)

CNE and CME Origination: June 1st, 2017
CNE and CME Review: September 1st, 2023
CNE and CME Expiration: August 31st, 2026 (3rd Edition)

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Steps to Acquire CE for this Lesson:

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3rd Edition

This is a substantial revision of the original Lesson. The previous edition was titled Drug Interactions with Antiretroviral Medications and available until September 1st, 2023.

Learning Objectives

  • Explain the difference between pharmacokinetics and pharmacodynamics
  • Access resources for checking drug interactions that involve antiretroviral medications
  • Identify commonly used antiretroviral medications that often cause significant drug interactions
  • Discuss how antiretroviral medications can increase or decrease levels of some medications when coadministered
  • Describe potential drug interactions between antiretroviral medications and medications commonly used to treat comorbid conditions

Lesson Contributors

Authors

John J. Faragon, PharmD, BCPS, AAHIV-P
John J. Faragon, PharmD, BCPS
Pharmacist, Albany Medical Center
Regional Pharmacy Director
Northeast/Caribbean AETC
Disclosures:
Consulting fees: ViiV Healthcare
Speakers Bureau: Gilead Sciences
The relevant financial relationship was mitigated.
Jehan Z. Budak, MD
Jehan Z. Budak, MD
Assistant Professor of Medicine
Division of Allergy & Infectious Diseases
University of Washington
Disclosures:
None

Reviewers

David H. Spach, MD
David H. Spach, MD
Professor of Medicine
Division of Allergy & Infectious Diseases
University of Washington
Disclosures:
None
Brian R. Wood, MD
Brian R. Wood, MD
Professor of Medicine
Division of Allergy & Infectious Diseases
University of Washington
Disclosures:
None

Lesson Plan

1Topic 1 Overview

2Topic 2 Acid Suppressive Therapy and Supplements

3Topic 3 Antimycobacterials

4Topic 4 Cardiovascular Medications

5Topic 5 Corticosteroids

6Topic 6 Hepatitis C Treatments

7Topic 7 HMG-CoA Reductase Inhibitors (Statins)

8Topic 8 Mental Health Medications

9Topic 9 Opioid Agonist Therapy

10Topic 10 Oral Anticoagulants and Antiplatelet Therapy

11Topic 11 Phosphodiesterase Type 5 (PDE5) Inhibitors

12Topic 12 Miscellaneous Interactions

13Topic 13 Summary Points

Lesson Quiz Drug Interactions with Antiretroviral Medications Quiz

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