Antiretroviral Therapy

Self-StudyAntiretroviral Therapy

Antiretroviral Therapy

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About Antiretroviral Therapy Self-Study Module

Core Competency

Apply Evidence-Based Antiretroviral Therapy for Persons with HIV

Target Audience

The Antiretroviral Therapy module is geared toward clinicians who provide antiretroviral therapy to persons with HIV, with an emphasis on initiating antiretroviral therapy and management of virologic failure.

Quick Reference

You can find all of the topics from this module in the openly accessible

Antiretroviral Therapy Quick Reference
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3rd Edition

This is a substantial revision of the original content. The previous edition was titled Antiretroviral Therapy and available until September 1st, 2023.

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The Antiretroviral Therapy module is geared toward clinicians who provide antiretroviral therapy to persons with HIV infection, with an emphasis on initiating antiretroviral therapy and management of virologic failure.

Self-Study Module Progress Tracker - 3rd Edition

	Lesson 1Antiretroviral Medications and Initial Therapy List the major classes of antiretroviral medications Explain the mechanism of action with each class of antiretroviral medications Summarize evidence supporting antiretroviral treatment of all persons with HIV Describe recommended antiretroviral regimens for treatment-naïve individuals and discuss factors to consider when selecting an initial regimen Discuss recommended laboratory studies to obtain at baseline and while monitoring response to therapy	Lesson 2Adverse Effects of Antiretroviral Medications Summarize common adverse effects associated with antiretroviral medications Identify serious adverse effects caused by antiretroviral therapy List appropriate baseline laboratory studies to perform when starting antiretroviral therapy Discuss frequency of types of laboratory tests for monitoring persons taking antiretroviral therapy Explain management strategies for antiretroviral-related adverse effects	Lesson 3Drug Interactions with Antiretroviral Medications Explain the difference between pharmacokinetics and pharmacodynamics Access resources for checking drug interactions that involve antiretroviral medications Identify commonly used antiretroviral medications that often cause significant drug interactions Discuss how antiretroviral medications can increase or decrease levels of some medications when coadministered Describe potential drug interactions between antiretroviral medications and medications commonly used to treat comorbid conditions	Lesson 4Switching or Simplifying Antiretroviral Therapy Discuss the rationale for switching or simplifying antiretroviral therapy Describe common situations to consider for simplifying antiretroviral therapy Explain why some antiretroviral medications generally warrant a switch to a newer agent List the two-drug regimens that have been FDA-approved for maintenance antiretroviral therapy Summarize key findings with studies involving a switch to an integrase strand transfer inhibitor	Lesson 5Evaluation and Management of Virologic Failure Describe the management of intermittent and persistently detectable HIV RNA levels in persons receiving antiretroviral therapy Discuss the indications for and types of resistance testing for patients with virologic failure Utilize an HIV resistance database tool to assist in the optimal selection of regimens in persons with HIV drug resistance Summarize concepts of resistance with different antiretroviral drug classes Explain key considerations when selecting a salvage antiretroviral regimen in persons with virologic failure
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CE Quiz

Self-Study Module Progress Tracker - 2nd Edition

2nd Edition. There is a newer edition of this Self-Study Module.

	Lesson 1Antiretroviral Medications and Initial Therapy 2nd Edition. There is a newer edition of this Lesson. This is your progress from the previous edition (2nd). List the major classes of antiretroviral medications Explain the mechanism of action with each class of antiretroviral medications Summarize evidence supporting antiretroviral treatment of all persons with HIV Describe recommended antiretroviral regimens for treatment-naïve individuals and discuss factors to consider when selecting an initial regimen Discuss recommended laboratory studies to obtain at baseline and while monitoring response to therapy	Lesson 2Adverse Effects of Antiretroviral Medications 2nd Edition. There is a newer edition of this Lesson. This is your progress from the previous edition (2nd). Summarize common adverse effects associated with antiretroviral medications Identify serious adverse effects caused by antiretroviral therapy List appropriate baseline laboratory studies to perform when starting antiretroviral therapy Discuss frequency of types of laboratory tests for monitoring persons taking antiretroviral therapy Explain management strategies for antiretroviral-related adverse effects	Lesson 3Drug Interactions with Antiretroviral Medications 2nd Edition. There is a newer edition of this Lesson. This is your progress from the previous edition (2nd). Explain the difference between pharmacokinetics and pharmacodynamics Access resources for checking drug interactions that involve antiretroviral medications Identify commonly used antiretroviral medications that often cause significant drug interactions Discuss how some antiretroviral increase levels of medications and others decrease levels of medications Describe several drug interactions involving antiretroviral medications and common therapeutic classes of drugs used to treat comorbid conditions	Lesson 4Switching or Simplifying Antiretroviral Therapy 2nd Edition. There is a newer edition of this Lesson. This is your progress from the previous edition (2nd). Discuss the rationale for switching or simplifying antiretroviral therapy Describe common situations to consider for simplifying antiretroviral therapy Explain why some antiretroviral medications generally warrant a switch to a newer agent List the two-drug regimens that have been FDA-approved for maintenance antiretroviral therapy Summarize key findings with studies involving a switch to an integrase strand transfer inhibitor	Lesson 5Evaluation and Management of Virologic Failure 2nd Edition. There is a newer edition of this Lesson. This is your progress from the previous edition (2nd). Describe the management of intermittent and persistently detectable HIV RNA levels in persons receiving antiretroviral therapy Discuss the indications for and types of resistance testing for patients with virologic failure Utilize an HIV resistance database tool to assist in the optimal selection of regimens in persons with HIV drug resistance Summarize concepts of resistance with different antiretroviral drug classes Explain key considerations when selecting a salvage antiretroviral regimen in persons with virologic failure
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Topic 9
Topic 10
Topic 11
Topic 12
Topic 13
Topic 14
Topic 15
CE Quiz

Self-Study Module Progress Tracker - 1st Edition

1st Edition. There is a newer edition of this Self-Study Module.

	Lesson 1Antiretroviral Medications and Initial Therapy 2nd Edition. There is a newer edition of this Lesson. This is your progress from the previous edition (2nd). List the major classes of antiretroviral medications Explain the mechanism of action with each class of antiretroviral medications Summarize evidence supporting antiretroviral treatment of all persons with HIV Describe recommended antiretroviral regimens for treatment-naïve individuals and discuss factors to consider when selecting an initial regimen Discuss recommended laboratory studies to obtain at baseline and while monitoring response to therapy	Lesson 2Adverse Effects of Antiretroviral Medications 2nd Edition. There is a newer edition of this Lesson. This is your progress from the previous edition (2nd). Summarize common adverse effects associated with antiretroviral medications Identify serious adverse effects caused by antiretroviral therapy List appropriate baseline laboratory studies to perform when starting antiretroviral therapy Discuss frequency of types of laboratory tests for monitoring persons taking antiretroviral therapy Explain management strategies for antiretroviral-related adverse effects	Lesson 3Drug Interactions with Antiretroviral Medications 2nd Edition. There is a newer edition of this Lesson. This is your progress from the previous edition (2nd). Explain the difference between pharmacokinetics and pharmacodynamics Access resources for checking drug interactions that involve antiretroviral medications Identify commonly used antiretroviral medications that often cause significant drug interactions Discuss how some antiretroviral increase levels of medications and others decrease levels of medications Describe several drug interactions involving antiretroviral medications and common therapeutic classes of drugs used to treat comorbid conditions	Lesson 4Switching or Simplifying Antiretroviral Therapy 2nd Edition. There is a newer edition of this Lesson. This is your progress from the previous edition (2nd). Discuss the rationale for switching or simplifying antiretroviral therapy Describe common situations to consider for simplifying antiretroviral therapy Explain why some antiretroviral medications generally warrant a switch to a newer agent List the two-drug regimens that have been FDA-approved for maintenance antiretroviral therapy Summarize key findings with studies involving a switch to an integrase strand transfer inhibitor	Lesson 5Evaluation and Management of Virologic Failure 2nd Edition. There is a newer edition of this Lesson. This is your progress from the previous edition (2nd). Describe the management of intermittent and persistently detectable HIV RNA levels in persons receiving antiretroviral therapy Discuss the indications for and types of resistance testing for patients with virologic failure Utilize an HIV resistance database tool to assist in the optimal selection of regimens in persons with HIV drug resistance Summarize concepts of resistance with different antiretroviral drug classes Explain key considerations when selecting a salvage antiretroviral regimen in persons with virologic failure
Topic 1
Topic 2
Topic 3
Topic 4
Topic 5
Topic 6
Topic 7
Topic 8
Topic 9
Topic 10
Topic 11
Topic 12
Topic 13
Topic 14
Topic 15
CE Quiz

Single-Tablet Regimens

Long-Acting Injectable Regimens

Capsid Inhibitors

Entry Inhibitors

Integrase Strand Transfer Inhibitors (INSTI)

Nucleoside Reverse Transcriptase Inhibitors (NRTI)

Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTI)

Protease Inhibitors (PI)

Pharmacokinetic Enhancers

Self-Study Module3rd EditionCNE/CME Available

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Lessons

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Self-Study Module3rd EditionCNE/CME Available

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Self-Study Module3rd EditionCNE/CME Available

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Self-StudyAntiretroviral Therapy