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HIV Diagnostic TestingQuestion 5/10

A 24-year-old man who has sex with men is seen in the emergency room for evaluation of fever, sore throat, lymphadenopathy, and severe fatigue. As part of the evaluation, he has HIV testing and the initial HIV-1/2 antigen-antibody assay test is reactive. The laboratory reflexively performs an HIV-1/HIV-2 supplemental (differentiation) assay and it is non-reactive.

Which one of the following should be the next step to resolve the discordant HIV test results?

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Question Last Updated
February 26th, 2026

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