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Acute and Recent HIV InfectionQuestion 3/5

A 32-year-old man is evaluated in an emergency room with a severe “viral syndrome” and the clinician considers acute HIV in the differential diagnosis.

Which cluster of clinical manifestations best describes a typical presentation for persons with acute HIV?

Figure 1. Clinical Manifestations Associated with Acute HIV
Source: Vanhems P, Hughes J, Collier AC, et al. Comparison of clinical features, CD4 and CD8 responses among patients with acute HIV-1 infection from Geneva, Seattle and Sydney. AIDS. 2000;14:375-81.
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Question Last Updated
May 3rd, 2026

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