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HIV Clinical Care Question Bank

Sexually Transmitted InfectionsQuestion 15/20

A 36-year-old woman with HIV presents to clinic to establish care. Routine screening for sexually transmitted infections, including Trichomonas vaginalis, is done and is positive for T. vaginalis.

Which one of the following is recommended to treat trichomoniasis in women with HIV?

In this trial women with HIV who were diagnosed with trichomoniasis were randomized to receive either metronidazole 500 mg orally twice daily for 7 days or metronidazole 2 g orally in a single dose. Women receiving the single-dose therapy clearly had higher failure rates.
Figure 1. Treatment of Trichomoniasis in Women with HIV with Single Dose or 7-Day Course of Metronidazole
In this trial women with HIV who were diagnosed with trichomoniasis were randomized to receive either metronidazole 500 mg orally twice daily for 7 days or metronidazole 2 g orally in a single dose. Women receiving the single-dose therapy clearly had higher failure rates.
Souce: Kissinger P, Mena L, Levison J, et al. A randomized trial: a single versus 7-day dose of metronidazole for the treatment of Trichomonas vaginalis among HIV-infected women. J Acquir Immune Defic Syndr. 2010;55;565-71.
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Question Last Updated
May 8th, 2026

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