A 43-year-old woman with chronic HIV returns to clinic for a follow-up visit. Recent laboratory studies show an aspartate aminotransferase (AST) level of 92 U/L, negative hepatis B surface antibody, and positive hepatitis B surface antigen (HBsAg). Testing for hepatitis C antibody was negative. She had an AST to Platelet Ratio Index (APRI) score of 4.6; an abdominal ultrasound performed 6 weeks prior showed a nodular cirrhotic liver.