A 55-year-old man with HIV returns to the clinic for management of severe hypertriglyceridemia. He has a CD4 count of 304 cells/mm³ and an undetectable HIV RNA level. He is taking dolutegravir and tenofovir DF-emtricitabine. Six months ago, a fasting lipid panel showed triglycerides of 1,130 mg/dL, high-density lipoprotein (HDL) of 25 mg/dL, and low-density lipoprotein (LDL) was unable to be calculated. Initially, he did not want pharmacotherapy, so he implemented a low-fat diet and increased his daily exercise. After 6 months, there was no improvement in the triglyceride levels, and he now agrees to take a medication for his elevated triglyceride levels. He does not have diabetes, liver disease, renal disease, or hypothyroidism. He is not taking any other medication, and he has a very low alcohol intake.