At approximately 11:30 p.m., a 32-year-old neurosurgery resident sustained a scalpel cut on the tip of his left fifth finger during an emergency brain surgery involving a patient with HIV. The scalpel had visible blood on it prior to the surgeon sustaining the cut. The scalpel injury occurred about 30 minutes into a complex surgery estimated to last 4 to 5 hours total. The source patient is taking bictegravir-tenofovir alafenamide-emtricitabine, but no recent results for an HIV RNA level are available. The surgeon scrubs out of the case and thoroughly washes the scalpel injury wound with soap and water. The scalpel cut on the finger is shallow but approximately 0.5 cm long; initial bleeding is stopped after pressure is applied to the wound.