Figure 1. Death and Disease Progression in Infants Receiving Early or Deferred Antiretroviral Therapy
In this clinical trial, investigators randomized infants with HIV infection who were 6 to 12 weeks of age to receive early antiretroviral therapy versus deferred therapy (based on CD4-related criteria). As shown in this graph, the group in the deferred treatment group (orange bars) had significantly higher rate of death and disease progression than those who received early treatment (blue bars).
Source: Violari A, Cotton MF, Gibb DM, et al. Early antiretroviral therapy and mortality among HIV-infected infants. N Engl J Med. 2008;359:2233-44.
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Question Last Updated
February 2nd, 2025
February 2nd, 2025
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