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- Module 3 Overview
Antiretroviral Therapy - 0%Lesson 1
Antiretroviral Medications and Initial TherapyActivities- 0%Lesson 2
Adverse Effects of Antiretroviral MedicationsActivities- 0%Lesson 3
Drug Interactions with Antiretroviral MedicationsLesson 5. Evaluation and Management of Virologic Failure
Learning Objective Performance Indicators
- Describe the management of intermittent and persistently detectable HIV RNA levels in persons receiving antiretroviral therapy
- Discuss the indications for and types of resistance testing for patients with virologic failure
- Utilize an HIV resistance database tool to assist in the optimal selection of regimens in persons with HIV drug resistance
- Summarize concepts of resistance with different antiretroviral drug classes
- Explain key considerations when selecting a salvage antiretroviral regimen in persons with virologic failure
About this Lesson
Learning Objective Performance Indicators
- Describe the management of intermittent and persistently detectable HIV RNA levels in persons receiving antiretroviral therapy
- Discuss the indications for and types of resistance testing for patients with virologic failure
- Utilize an HIV resistance database tool to assist in the optimal selection of regimens in persons with HIV drug resistance
- Summarize concepts of resistance with different antiretroviral drug classes
- Explain key considerations when selecting a salvage antiretroviral regimen in persons with virologic failure
Activities in this Lesson
- Quick ReferenceEvaluation and Management of Virologic Failure Core Concepts
- Introduction
- Definition of Terms Related to Virologic Responses
- Causes of Virologic Failure
- Approach to Detectable HIV RNA Levels
- HIV Drug Resistance Assays
- Indications for HIV Drug-Resistance Testing
- Interpretation of Drug-Resistance Assays
- Nucleoside Reverse Transcriptase Inhibitor Resistance
- Non-Nucleoside Reverse Transcriptase Inhibitor Resistance
- Integrase Strand Transfer Inhibitor Resistance
- Protease Inhibitor Resistance
- Entry Inhibitor Resistance
- Capsid Inhibitors
- General Approach to Management of Virologic Failure
- Summary Points
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CME provided byUniversity of Alabama Birmingham
CNE provided byUniversity of Washington School of Nursing
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